Mitochondrial Phenotypes and β-ll Spectrin Expression in Cancer Cells as a result of TGF-β Induction
Cellular and Molecular Biology and Biochemistry
Ajax Glenn-Grambo
Anysa Medrano
- Grade:
- 12
- Teacher:
- Viktoriya Yurkiv
This project explores how TGF-β signlaing affects pancreatic cancer cells by disrupting β-ll spectrin, a protein that helps maintain cell structure and signaling. Changes in β-ll spectrin were linked to mitochondrial damage, which can lead to cancer cell death and may serve as an early indicator of PDAC.
This was an advanced level of research, and it is clear that you knew the subject very well. Your data analysis clearly tied in to the hypothesis and also left open future hypothesis testing.
Thank you for your work in this important issue that impacts so many lives!